Vol. 8, Issue 4 (2020)
Erythropoietin prevents liver injury in septic mice
Author(s): K Kannan, S Choudhury, T Ramasamy, M Kesavan, S Parida and TU Singh
Abstract: In the present study, the effect of erythropoietin in liver of septic mice was investigated. Sepsis was induced by caecal ligation and puncture model. After 20+2 hrs of surgery, blood and liver samples were collected. Plasma TNF-α, IL-1β, Serum AST, ALT and Liver lipid peroxidation, myeloperoxidase, thiols was estimated and histopathology was performed. Post-treatment with erythropoietin ameliorated the sepsis induced changes in hepatic and systemic inflammatory changes in mice.
DOI: 10.22271/chemi.2020.v8.i4au.10224
Pages: 3720-3725 | 410 Views 98 Downloads
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How to cite this article:
K Kannan, S Choudhury, T Ramasamy, M Kesavan, S Parida, TU Singh. Erythropoietin prevents liver injury in septic mice. Int J Chem Stud 2020;8(4):3720-3725. DOI: 10.22271/chemi.2020.v8.i4au.10224
