Vol. 9, Issue 1 (2021)
Electron-transfer oxidation of Organo-cuprates with Benzophenone: Synthesis of Biaryls
Author(s): M Jalilur Rahman, Md. Abdul Malek, Rehana Pervin and Shameem Ara Begum
Abstract: A mild and simple way to synthesize Biaryls from aryl bromides via formation of organo-cuprate complexes has been developed. The Organo-cuprates {Ar2CuMgBr.Mg(I)Br}, generated from Arylmagnesium bromide and half equivalent of copper(I) iodide in dry THF at lower temperature under nitrogen, underwent electron-transfer oxidation with an aryl ketone benzophenone producing homo-coupled Biaryls in moderate yields. Aryl bromides either with electron-donating or with electron-withdrawing substituents were smoothly transformed into the corresponding Biaryls through formation of aryl Grignard reagents and Organo-cuprate complexes in a one pot reaction under this electron-transfer oxidation procedure.
DOI: 10.22271/chemi.2021.v9.i1a.11596
Pages: 41-44 | 928 Views 190 Downloads
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How to cite this article:
M Jalilur Rahman, Md. Abdul Malek, Rehana Pervin, Shameem Ara Begum. Electron-transfer oxidation of Organo-cuprates with Benzophenone: Synthesis of Biaryls. Int J Chem Stud 2021;9(1):41-44. DOI: 10.22271/chemi.2021.v9.i1a.11596
