Vol. 7, Issue 4 (2019)
Cerulein induced acute pancreatitis through activation of oxidation stress and inflammation
Author(s): Guda Swapna
Abstract: Cerulein induced acute pancreatitis, is the widely used experimental model for the induction of AP as it is economical with high reproducibility. Cerulein being a cholecystokinin (CCK) analogue, aids in the secretion of digestive enzymes thereby hyperstimulation of the exocrine pancreas with high cerulein dose stimulates the pancreas resulting in the upregulation of the inflammatory mechanisms through activation of NFκB and release of Reactive Oxygen species (ROS) which go hand in hand that lead to acute pancreatitis condition.
Pages: 3257-3259 | 128 Views 49 Downloads
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How to cite this article:
Guda Swapna. Cerulein induced acute pancreatitis through activation of oxidation stress and inflammation. Int J Chem Stud 2019;7(4):3257-3259.
