Vol. 11, Issue 6 (2023)
Synthesis and biological investigation of novel heterocyclic thiosemicarbazone silver (I) complexes as potent antimicrobial agents
Author(s): Elvan Hasanoğlu Özkan, Nurdan Kurnaz Yetim, Hatice Öğütcü and Dilek Nartop
Abstract:
Herein, new heterocyclic thiosemicarbazone silver (I) complexes (Tsc1, Tsc2, Tsc3, Tsc4) were synthesized by the template method, and their structures were determined using some spectral techniques: element analysis, Fourier transform infrared spectra (FT-IR), proton nuclear magnetic resonance (1H-NMR), thermogravimetric analysis (TG-DTA), organic elemental analysis, and magnetic susceptibility measurements. The biological activities of the newly synthesized heterocyclic thiosemicarbazone silver (I) complexes were investigated as potent antimicrobial agents against some disease-causing pathogens. For this purpose, the well-diffusion method was used. The biological activity results demonstrated that all novel heterocyclic thiosemicarbazone silver (I) complexes have high or moderate inhibitory activity of the tested pathogenic strains.
Graphical Abstract
![11-6-20](https://www.chemijournal.com/up/PNG_20231212_115237.png)
DOI: 10.22271/chemi.2023.v11.i6a.12367
Pages: 35-41 | 343 Views 163 Downloads
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How to cite this article:
Elvan Hasanoğlu Özkan, Nurdan Kurnaz Yetim, Hatice Öğütcü, Dilek Nartop. Synthesis and biological investigation of novel heterocyclic thiosemicarbazone silver (I) complexes as potent antimicrobial agents. Int J Chem Stud 2023;11(6):35-41. DOI: 10.22271/chemi.2023.v11.i6a.12367