Vol. 6, Issue 6 (2018)
A journey towards systems biology: Biocomputing of hi-throughput omics data: A national training workshop report-2018
Author(s): Gohar Taj, Apoorv Tiwari, Rutash Kumar, BR Singh, Ashutosh Dubey, SD Samantaray and Anil Kumar Gaur
Abstract: Recent years, rapid developments in several omics platforms and next generation sequencing technology have generated a huge amount of biological data about plants. Systems biology aims to develop and use well-organized and efficient algorithms, data structure, visualization, and communication tools for the integration of biological data with the goal of computational modeling and simulation. Plant systems biology studied by some major steps including analysis of gene, protein sequences, and informational pathway, integration of data, and formulating mathematical models that describe the structure of system and its response to individual perturbations. With advances in proteomics and regularly updated open access databases, bioinformatics will contribute to those processes by providing purposeful information of target candidates and correlating this information to biological pathways. More studies are currently being directed towards unraveling the delicate network of interactions that govern cellular and development processes in organisms. Success in this exciting endeavor will be possible only with collaborative and cross-disciplinary efforts in close association with scientists in disciplines such as computer science, statistics, and information visualization. Once this collaboration is matured, it will be possible to understand and predict whole-plant performance in a given set of conditions. Finally, it will be possible to use such models in a predictive mode which can be applied for improving the desirable traits associated with agricultural crops.
Pages: 2751-2756 | 351 Views 64 Downloads
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How to cite this article:
Gohar Taj, Apoorv Tiwari, Rutash Kumar, BR Singh, Ashutosh Dubey, SD Samantaray, Anil Kumar Gaur. A journey towards systems biology: Biocomputing of hi-throughput omics data: A national training workshop report-2018. Int J Chem Stud 2018;6(6):2751-2756.
