Vol. 7, Issue 1 (2019)
Evaluation of guaifenesin-ketamine-xylazine and diazepam-ketamine-xylazine triple drip for gelding in equines
Author(s): SS Pitlawar, PT Jadhao, BM Gahlod, SV Upadhye, MS Dhakate, SB Akhare and NV Kurkure
Abstract: The study was aimed to evaluate comparison between two different anaesthetic combinations using guaifenesin and diazepam in xylazine-ketamine induced total intravenous anaesthesia in equine for gelding. The anaesthetic parameters included quality of total intravenous anaesthesia, quality of muscle relaxation and quality of recovery of anaesthesia in Group I and Group II. The anaesthetic parameters were recorded at pre induction (0 min), after induction at 30 minutes, immediately after the complete recovery and 24 hrs after complete recovery of anaesthesia. The study suggested that neither of drug combinations of GKX and DKX produced no any adverse effect on the vital organs of the body and were acceptable for maintenance of anaesthesia in horses for gelding up to 30 minutes duration under field conditions. The quality of anaesthesia was overall excellent to satisfactory in both the groups with loss of gag reflexes. Overall, 90% horses from Group I revealed excellent muscle relaxation whereas, in Group II, 60% horses showed excellent muscle relaxation and 40% showed good degree of muscle relaxation. In Group I the mean duration of anaesthesia was 33.60±1.78 min and mean surgical operating time was 28.50±3.46 min. In Group II, the mean duration of anaesthesia and surgical operating time was 30.40±0.30 min and 23.70±2.00 min, respectively. The quality of recovery in horses of Group I was fast, smooth in 70% and smooth and prolonged recovery in 30% of the horses. Whereas, varied recovery was observed in group II.
![Loss of gag reflex during anaesthesia](https://www.chemijournal.com/up/graphics/4832/19121801112648320.png)
Fig. 1: Loss of gag reflex during anaesthesia
![Lacrimation during light level of anaesthesia](https://www.chemijournal.com/up/graphics/4832/19121801112648321.png)
Fig. 2: Lacrimation during light level of anaesthesia
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How to cite this article:
SS Pitlawar, PT Jadhao, BM Gahlod, SV Upadhye, MS Dhakate, SB Akhare, NV Kurkure. Evaluation of guaifenesin-ketamine-xylazine and diazepam-ketamine-xylazine triple drip for gelding in equines. Int J Chem Stud 2019;7(1):975-979.