Vol. 7, Issue 1 (2019)
Phytochemical analysis, in-vitro antioxidant, anti-inflammatory and insect antifeeding activity of methanolic extract of Limnophila indica (L.) Druce
Author(s): Randeep Kumar, Ravendra Kumar, Bahaar Anjum, Om Prakash, Archana Joshi, AK Pant, Chenesh Patel and RM Srivastava
Abstract: Present research reports the chemical composition, total phenolics, antioxidant and insect antifeeding activity of the methanolic extract of the Limnophila indica (L.) Druce. GC-MS analysis of the extract led to identification of fifty-two components constituting 74.3% of total extract composition mainly dominated by β-monolinolein (12.9%) and linoelaidic acid (11.6%). The extract possesses significant amount of total phenolics, flavonoids and ortho-dihydric phenols. Antioxidant activity assessment via NO radical scavenging, DPPH radical scavenging, metal chelating of Fe+2, reducing power activity reveals the plant possesses potential antioxidant property with respective IC50 values 42.48±1.87, 31.98±0.59, 59.02±0.73, 53.28±1.21 µg/ml. In-vitro anti-inflammatory activity screening of the extract revealed the extract acting as potentially active anti-inflammatory agent with IB50 value 43.98±2.66. Insect antifeeding activity monitored through no choice leaf dip method against Spilosoma obliqua resulting dose and time dependent antifeeding activity.
Fig. 1: Gas chromatogram of methanolic extract of L. indica.
Pages: 1691-1696 | 355 Views 85 Downloads
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How to cite this article:
Randeep Kumar, Ravendra Kumar, Bahaar Anjum, Om Prakash, Archana Joshi, AK Pant, Chenesh Patel, RM Srivastava. Phytochemical analysis, in-vitro antioxidant, anti-inflammatory and insect antifeeding activity of methanolic extract of Limnophila indica (L.) Druce. Int J Chem Stud 2019;7(1):1691-1696.
