Vol. 7, Issue 4 (2019)
Mosla dianthera (Buch.-Ham. ex Roxb.) Maxim: Chemical compositions, biochemical assay, in vitro antioxidant and anti-inflammatory activity of chloroform extract
Author(s): Jeewanti Kanyal, OM Prakash, Ravendra Kumar, DS Rawat and AK Pant
Abstract: Mosla dianthera Maxim. is an annual aromatic plant of family Lamiaceae used in traditional medicine and as spice in foods. The present study is on the investigation of chemical compositions, biochemical assay, antioxidant and in vitro anti-inflammatory activities of the chloroform extract of Mosla dianthera. The GC-MS analysis led to identification of fifty five compounds contributing 84.6% of the total extract of which tetrapentacontane (21.8%), 7-methoxy-5-hydroxyflavone (8.1%) and hexatriacontane (6.6%) were identified as the major components. The extract possessed good quantity of total phenolics (19.01±0.25 mg/g of GAE) flavonoids (41.04±0.13 mg/g of CNE) and orthodihydric phenols (7.43±0.92 mg/g of CLE). The in vitro antioxidant activity in term of DPPH radical scavenging, hydroxyl radical scavenging, nitric oxide radical scavenging, superoxide radical scavenging, reducing power and metal chelating activity in term of IC50/RP50 values were found to be IC50= 169.56±0 µg/mL, IC50= 124.66±0.79 µg/mL, IC50= 144.78±0.11 µg/mL, IC50= 132.44±0.06 µg/mL, RP50=204.21±0.75 µg/mL and IC50= 231.81 ±0.14 µg/mL respectively. The extract also exhibited a potential source of in vitro anti-inflammatory activity with IC50= 120.83±0.73 µg/mL.
Pages: 2807-2813 | 213 Views 28 Downloads
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How to cite this article:
Jeewanti Kanyal, OM Prakash, Ravendra Kumar, DS Rawat, AK Pant. Mosla dianthera (Buch.-Ham. ex Roxb.) Maxim: Chemical compositions, biochemical assay, in vitro antioxidant and anti-inflammatory activity of chloroform extract. Int J Chem Stud 2019;7(4):2807-2813.
