Vol. 7, Issue 6 (2019)
Hyperfibrinogenemia in thrombocytopenic dogs with Babesia gibsoni: Evaluation of fibrinogen as a diagnostic indicator
Author(s): Pothiappan P, Nagarajan B, Baranidharan GR, Vairamuthu S, Jayathangaraj MG and Tirumurugaan KG
Abstract: Fibrinogen is an essential component of the haemostatic process, with key roles both in plasmatic clot formation and as a cofactor for the aggregation of platelets. Thirty thrombocytopenic dogs (<25,000 cells/cmm) of different signalments affected with Babesia gibsoni with signs of bleeding including echymosis, pupura, hematuria, scleral haemorrhage, melena, epistaxis were included for this study. The average mean and SE values of fibrinogen in healthy and affected animals were 119.58 ± 3.82 mg/dl and 394.81 ± 6.89 mg/dl. Hyperfibrinogenemia, in our study seems predominant in dogs affected with babesia gibsoni which could be attributed due to endothelial damage and acute inflammation. Measurement of plasma fibrinogen concentration proved useful in the evaluation of coagulopathies due to babesia and inflammatory disorders. It can be considered as one of the routine test in the diagnosis and to assess the severity of progression of coagulative disorders in canine vector-borne diseases.
Pages: 330-331 | 413 Views 83 Downloads
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How to cite this article:
Pothiappan P, Nagarajan B, Baranidharan GR, Vairamuthu S, Jayathangaraj MG, Tirumurugaan KG. Hyperfibrinogenemia in thrombocytopenic dogs with Babesia gibsoni: Evaluation of fibrinogen as a diagnostic indicator. Int J Chem Stud 2019;7(6):330-331.
