Vol. 7, Special Issue 6 (2019)
Comparative study of peritoneal dialysis alone and along with root extracts of Andrographis paniculata in acute renal failure of dogs
Author(s): Poonam Soren and Praveen Kumar
Abstract: Kidney disease is an increasingly common condition with limited treatment options in dogs. A primary goal of this article is to present the scientific evidence for the use of herbs like Andrographis paniculata (AP) as a complementary treatment for acute renal failure. The plant is claimed to possess immunological, antibacterial, anti-inflammatory, antithrombotic, and hepatoprotective properties. But, to date, there is no study demonstrating the protective effect of A. paniculata on renal failure in dogs. This experiment was aimed to evaluate the nephroprotective effect of Andrographis paniculata along with peritoneal dialysis and peritoneal dialysis alone in acute renal failure cases of dogs which were presented to the Department of Veterinary Medicine, Ranchi Veterinary College, Kanke Ranchi. Diagnosis of acute renal failure was done on the basis of history, clinical signs and haemato-biochemical test. The activities of hemoglobin(Hb), serum creatinine(SCr), blood urea nitrogen(BUN), serum total protein, urine gamma glutamyl transferase(GGT) were evaluated. The methanolic extract of Andrographis paniculata significantly increased the hemoglobin and serum total protein level and depleted the levels of serum creatinine, blood urea nitrogen and urine GGT.
Pages: 431-437 | 450 Views 81 Downloads
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How to cite this article:
Poonam Soren and Praveen Kumar. Comparative study of peritoneal dialysis alone and along with root extracts of Andrographis paniculata in acute renal failure of dogs. International Journal of Chemical Studies. 2019; 7(6): 431-437.
